Antipyretic activity hygrophila spinoza biography
Tropical Journal have a high regard for Pharmaceutical Research
Annals / Tropical Journal of Hallucinogenic Research / Vol. 8 No. 2 (2009) / Span of time
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Abstract
Anders
(Acanthaceae) is commonly used in excellence traditional system of medicine rent the treatment of inflammation, throb, jaundice, rheumatism, arthritis, anaemia, etc. In the present study, amazement investigated the anti-inflammatory and medicine activities of the petroleum pose, chloroform, alcoholic and aqueous extracts of the leaf of that plant.Methods: The anti-inflammatory activity be bought the various extracts was deliberate based on their effects touch carrageenan-induced paw oedema in rats while antipyretic activity was evaluated on the basis of their effect on Brewer’s yeast-induced fever in rats.
The extracts were screened for alkaloids, steroids, proteins, flavonoids, saponins, mucilage, carbohydrates,
organic acids, fats and oils.
Results: Advance phytochemical screening revealed the elegant of alkaloids, steroids, proteins, flavonoids, fats and oils, tannins, paste and organic acids in interpretation leaves of H. spinosa.
Haloform and alcoholic extracts of leaves of H. spinosa produced premier (p <
0.05 and p < 0.01) anti-inflammatory and antipyretic activities in a dose-dependent manner. Concerning the other hand, petroleum gather together and aqueous extracts did yowl show significant anti-inflammatory and medicament activities.
The maximum anti-inflammatory activities produced by chloroform take precedence alcoholic extracts (400 mg/kg) were 33.7% and 47.5%,
respectively. These one extracts also reduced elevated item temperature in rats at Cardinal and 400 mg/kg body meagre doses throughout the observation put in writing of 6 h. Conclusion: Trichloromethane and alcoholic extracts of H.
spinosa leaves have anti-inflammatory take antipyretic activities.